Research Techniques in Medicinal Chemistry
(30:715:451 or 16:663:501)
Course Instructor
- Matthew Moschitto, Ph.D., (Coordinator)
- Office: Room 330 EMSOP (PH)
- Phone: 848-445-5382
- Email: m.moschitto@pharmacy.rutgers.edu
Times and Location
T, TH: 5:00 – 6:20 PM, PH 249
Fall 2021 Exam Schedule
Exam # 1 – Tuesday, October 12th Time TBD
Exam # 2 – Tuesday, November 9th Time TBD
Final Exam – TBD
Course Description: This is an intensive course composed of medicinal and physical organic chemistry principles and techniques and will provide a basis for students to enter and succeed in a medicinal chemistry laboratory setting. The course will cover physical organic principles, reaction mechanisms, and their interrelation with medicinal chemistry and enzymology. The organic chemical principles will cover the conceptual aspects of orbitals and bonding, stereochemistry, conformational analysis, acid/base theory, and substituent effects. Concepts surrounding elimination reactions, nucleophilic and electrophilic substitution using stereoelectronic and orbital theory, and general reaction mechanisms will be explored. Lastly, the course will cover techniques needed in a medicinal chemistry laboratory including assay development and interpretation, as well as synthetic organic techniques and strategies. This course is designed as an introductory graduate course or an advanced undergraduate course for students who have completed two semesters of organic chemistry with an associated laboratory component.
Research Techniques in Medicinal Chemistry
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