Pharmaceutical Chemistry (30:715:307)
- Longqin Hu, Ph.D., (Coordinator) PH Room 314
- Matthew Moschitto, Ph.D., Room 330
- Michael Totleben, Ph.D.
Times and Location
M W: 6:55- 7:50 PM, PH 130
*There will be a weekly quiz on Mondays beginning at 6:15pm in PH 130 per the schedule printed on the Canvas course website using lockdown browser via Quizzes on Canvas (must bring your own laptop).
Fall 2022 Exam Schedule
Exam # 1 – Monday, October 10, 2022, 6:55 PM, PH 130/131 IN-PERSON using Lockdown Browser via Quizzes on Canvas (must bring your own laptop)
Exam # 2 – Monday, November 14, 2022, 6:55 PM, PH 130/131 IN-PERSON using Lockdown Browser via Quizzes on Canvas (must bring your own laptop)
Exam #3 – TBD, PH 130/131 IN-PERSON using Lockdown Browser via Quizzes on Canvas (must bring your own laptop)
Cumulative Final Exam (Optional for students w/>70%) – TBD, IN-PERSON using Lockdown Browser (Must bring your own laptop)
Organic Chemistry Concepts and Applications for Medicinal Chemistry, Joseph E. Rice, Academic Press, 2014, Softcover; ISBN 9780128007396 or eBook; ISBN 9780128008324.
Reference Textbook: Pharmaceutical Analysis, A Textbook for Pharmacy Students and Pharmaceutical Chemists, 3rd Edition, David G. Watson, Elsevier, 2012, ISBN: 0702046213.
Course Description: The mission of the Pharmaceutical Chemistry course is to introduce students to the structure, properties, and analysis of pharmaceutical agents and metabolites as well as some fundamental techniques used for near patient testing and pharmacokinetic analysis. Topics include basic concepts in medicinal chemistry as well as methods of pharmaceutical and biomedical analysis: 1) the drug discovery and development process, 2) review of organic functional groups found in drug molecules, 3) drug-target interactions, 4) physicochemical properties related to drug action such as acid-base properties, equilibrium, and stereochemistry, 5) Chemistry of OTC inorganic drugs, 6) Effect of chemical structure on the metabolism of drug molecules, 7) Fundamentals of neurochemistry, and 8) Chromatographic (especially HPLC and LC-MS) analysis of pharmaceutical agents, metabolites, and clinical samples