Pharmaceutical Chemistry (30:715:307)


Times and Location

M W:  6:05 – 7:00 PM, PH 130

Fall 2018 Exam Schedule

Exam # 1 – Wednesday, Oct. 24, 2018, 6:00 PM, Room PH 130/131

Exam # 2 – Wednesday, Dec. 12, 2018, 6:00 PM, Room PH 130/131

Cumulative Final Exam – TBA  (Optional for students w/>70%)


Organic Chemistry Concepts and Applications for Medicinal Chemistry, Joseph E. Rice, Academic Press, 2014, Softcover; ISBN 9780128007396 or eBook; ISBN 9780128008324.

Reference Textbook: Pharmaceutical Analysis, A Textbook for Pharmacy Students and Pharmaceutical Chemists, 3rd Edition, David G. Watson, Elsevier, 2012, ISBN: 0702046213.

Course Description:  The mission of the Pharmaceutical Chemistry course is to introduce students to the structure, properties, and analysis of pharmaceutical agents and metabolites as well as some fundamental techniques used for near patient testing and pharmacokinetic analysis. Topics include basic concepts in medicinal chemistry as well as methods of pharmaceutical and biomedical analysis: 1) the drug discovery and development process, 2) review of organic functional groups found in drug molecules, 3) drug-target interactions, 4) physicochemical properties related to drug action such as acid-base properties, equilibrium, and stereochemistry, 5) Chemistry of OTC inorganic drugs, 6) Effect of chemical structure on the metabolism of drug molecules, 7) Fundamentals of neurochemistry, and 8) Chromatographic (especially HPLC and LC-MS) analysis of pharmaceutical agents, metabolites, and clinical samples



Pharmaceutical Chemistry