Edmond J. LaVoie, PhD
Professor Emeritus
Medicinal Chemistry
Education & Training
PhD - State University of New York, Buffalo, NYBS - Fordham University, Bronx, NY
Research Interests
Drug discovery and development, specifically the design of novel topoisomerase I and II targeting agents as anticancer agents. Studies have also been undertaken to develop agents that will selectively bind and stabilize G-quadruplex DNA and RNA. A new class of antibiotics for use against methicillin-resistant Staphylococcus aureus (MRSA) is also being explored for future development into the clinic. In light of increased resistance developing for agents used to prevent and treat influenza A infection, we are also engaged in studies on the development of a new class of antiviral agents. These agents specifically target the endonuclease enzyme of influenza A and prevent viral proliferation.