Graduate Program in Medicinal Chemistry Facilities

The Department of Medicinal Chemistry is equipped with a wide variety of modern instrumentation and equipment for conducting research in the design and synthesis of new therapeutic agents.

Department Equipment

• Advance 400 MHz nuclear magnetic resonance spectrometer (1H, 13C, 19F, 32P capable).
• Perkin Elmer polarimeter.
• Thermo-Nicolet Avatar 360 FT-IR.
• Agilent 1200 HPLC with various chiral columns.
• Waters Synapt G2 HRMS (ESI) with Waters Aquity HPLC.
• biosafety hoods.
• CO₂-jaceted incubator.
• Advanced ChemTech Model 90 peptide synthesizer.
• Agilent 5890 Series II GC.

In addition to Shared Departmental Equipment, individual laboratories in the Department of Medicinal Chemistry have access to a wide variety of synthetic and biochemical equipment.  Contact individual laboratories for details.  Equipment includes:

• INERT solvent system for dispensing anhydrous solvent (Moschitto).
• Shimadzu VP10A HPLC with autosampler with attached ThermoFisher TSQ Quantum mass spectrometer operating in ESI mode for compound analysis and reaction monitoring (Moschitto)
• Teledyne Isco NextGen 300 flash purification system for compound purification (Moschitto, Hu, Wang).
• Parr hydrogenator apparatus (Moschitto).
• Various photoreactor setups (Moschitto and Wang)
  • Penn PhD Photoreactor
  • Kessil Lamp Setups (395 nm and 440 nm).
• Various Agilent and Shimadzu LC/MS systems (Moschitto, Hu, Wang).
• Various Biotek Synergy plate readers (Moschitto and Wang.
• AKTA Explorer FPLC for protein purification (Moschitto).
• Beckman Coulter Floor centrifuge (Wang).

 University Facilities and Cores:

Beyond the department equipment and facilities, students also have access to Rutgers Core Facilities and Services. This includes:

Chemistry Department Analysis Core:

• Varian 300 and 500 MHz NMRs.
• Bruker Avance 500, 600, 700, and 800 NMRs.
• Xevo G2-X2 QTof MS.

Biological Mass Spectrometry Facility:

• Thermo Orbitrap Eclipse Tribrid Mass Spectrometer with a Dionex U-3000 Rapid Separation nano LC system.