Department Facilities and Equipment
The Department of Medicinal Chemistry is equipped with a wide variety of modern instrumentation and equipment for conducting research in the design and synthesis of new therapeutic agents.
Department Equipment
- Advance 400 MHz nuclear magnetic resonance spectrometer (1H, 13C, 19F, 32P capable).
- Perkin Elmer polarimeter.
- Thermo-Nicolet Avatar 360 FT-IR.
- Agilent 1200 HPLC with various chiral columns.
- Waters Synapt G2 HRMS (ESI) with Waters Aquity HPLC.
- biosafety hoods.
- CO2-jaceted incubator.
- Advanced ChemTech Model 90 peptide synthesizer.
- Agilent 5890 Series II GC.
In addition to Shared Departmental Equipment, individual laboratories in the Department of Medicinal Chemistry have access to a wide variety of synthetic and biochemical equipment. Contact individual laboratories for details. Equipment includes:
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- INERT solvent system for dispensing anhydrous solvent (Moschitto).
- Shimadzu VP10A HPLC with autosampler with attached ThermoFisher TSQ Quantum mass spectrometer operating in ESI mode for compound analysis and reaction monitoring (Moschitto)
- Teledyne Isco NextGen 300 flash purification system for compound purification (Moschitto, Hu, Wang).
- Parr hydrogenator apparatus (Moschitto).
- Various photoreactor setups (Moschitto and Wang)
- Penn PhD Photoreactor
- Kessil Lamp Setups (395 nm and 440 nm).
- Various Agilent and Shimadzu LC/MS systems (Moschitto, Hu, Wang).
- Various Biotek Synergy plate readers (Moschitto and Wang.
- AKTA Explorer FPLC for protein purification (Moschitto).
- Beckman Coulter Floor centrifuge (Wang).
University Facilities and Cores:
Beyond the department equipment and facilities, students also have access to Rutgers Core Facilities and Services. This includes:
Chemistry Department Analysis Core:
- Varian 300 and 500 MHz NMRs.
- Bruker Avance 500, 600, 700, and 800 NMRs.
- Xevo G2-X2 QTof MS.
Biological Mass Spectrometry Facility:
- Thermo Orbitrap Eclipse Tribrid Mass Spectrometer with a Dionex U-3000 Rapid Separation nano LC system.
