Jessie Yanxiang Guo, PhD

The Cancer Metabolism and Growth Research Program

2015 – 2018 – The NCI Transition Career Development Award (K22)

MD – Peking University Health Science Center, Beijing, China
PhD – Duke University, Durham, NC
MS – Institute of Basic Science, Beijing, China
BS – Peking University Health Science Center, Beijing, China
Post-Doctoral Fellowship – Eileen White Lab, Rutgers University, New Brunswick, NJ

My general research interests are to elucidate the mechanisms of tumorigenesis and identify potential targets for cancer therapy. Currently, research in my lab is focused on the field of cancer metabolism in KRAS-driven lung tumorigenesis. We expect to identify metabolic vulnerabilities in KRAS-driven lung tumor and determine if we can improve lung cancer treatment by targeting tumor specific metabolic pathways. Combination of genetically engineered mouse models, the state-of-the-art metabolomic and lipidomic analysis, and in vivo isotope tracing and metabolic flux analysis studies are being utilized to achieve these goals.

Associate Professor, Rutgers Cancer Institute of New Jersey, RBHS – Robert Wood Johnson Medical School, New Brunswick