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FACULTY PROFILE

Guofeng You, PhD
Distinguished Professor
Department of Pharmaceutics

Phone: (848) 445 6349
Fax: 732 445 3134
Email: gyou@rci.rutgers.edu

 

Bio

Guofeng You is a Distinguished Professor in the Department of Pharmaceutics, the Ernest Mario School of Pharmacy, Rutgers University. Her research interest focuses on the elucidation of the molecular, cellular and functional characteristics of drug/xenobiotic transporters, their implications in human physiology and diseases, and their applications to drug therapy. Dr. You has trained many Ph.D., M.S. students, and postdoctoral fellows, and has published numerous original research articles in the field of drug transport. Dr. You has served and is continuing to serve on several NIH panels, and is on the Editorial Board of Pharmaceutical Research and International Journal of Biochemistry and Molecular Biology.

Research

Molecular and Cellular Pharmacology, Drug/Xenobiotic Absorption, Distribution and Elimination, Membrane Transporters

Drug transporters mediate the absorption, distribution, and excretion of a diverse array of clinically important drugs, including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories, and therefore are critical to the survival of the mammalian species. The goal of Dr. You's research is to elucidate the molecular, cellular, and functional characteristics of these transporters, their implications in human physiology and diseases, and their applications to drug therapy. Techniques in molecular and cellular biology, physiology, biochemistry, and biophysics are used to investigate the transport mechanisms both in vitro and in vivo.  The knowledge gained from these studies will have significant impact on the future design of strategies aimed at maximizing therapeutic efficacy and minimizing toxicity, and will permit insight into the molecular, cellular, and clinical bases of renal, hepatic, neurological and fetal toxicity and disease.

View Dr. You's Representative Publications

Awards and Honors

2012 - 2014      Co-Editor, Book "Drug Transporters” to be published by Wiley & Son, NY, NY
2012 - 2014      Executive Council, Graduate School-New Brunswick, Rutgers University
2011 - 2012      Co-Chair, Mission, Planning & Evaluation sub-committee, ACPE Steering Committee,
                      School of Pharmacy, Rutgers University
2012                NIH Review Panel for COBRE Pilot Project Applications
2012                NIH Special Emphasis Review Panel for Program Project Grants
2008 - 2011      Executive Committee, Student and Postdoc Outreach and Development, American Association
                      of Pharmaceutical Scientists
2007-2011        NIH Study Section Permanent Member, Cellular and Molecular Biology of the Kidney
2011                NIH Special Emphasis Review Panel for Program Project Grants.
2011                Committee, Pharmaceutical Research Meritorious Manuscript Award, Pharmaceutical Research
2010                Co-Chair, Symposium “Transport Proteins I: Regulatory Mechanisms That Modulate
                       Drug Disposition and Response”, American Association of Pharmaceutical Scientists, Georgia.
2009-present     Editorial Board, International Journal of Biochemistry and Molecular Biology
2008-2012         Executive Committee, Drug Transport Focus Group, American Association of
                       Pharmaceutical Scientist
2006-present     Editorial Board, Pharmaceutical Research